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POLICIES AND CLINICAL GUIDELINES

CarepathRx policies and procedures provide our nursing partners with the strategy and guidelines needed to establish safe and effective infusion therapy in the home setting. 

A. GENERAL

  • Flushing Catheters NUR-001
  • Infusion Administration Best Practice Guidelines NUR-002 
  • IV Catheter Care – Quick Reference NUR-003 
  • Blood Culture Collection NUR-004
  • Drug Level Drawing Times NUR-005
  • Lab Draw Protocol NUR-006
  • Antimicrobial Lock Therapy Central Venous Access Device NUR-010
  • Management of Allergic/Anaphylactic Reactions NUR-012
  • IV Push Medication via Syringe NUR-013
  • Withdrawing Medication from a Vial NUR-014
  • Administration of Cathflo Activase in Adult Patient NUR-015
  • Aseptic Non-Touch Technique (ANTT) NUR-016
  • Algorithm for Notification of Pharmacist and Provider NUR-021
  • Infiltration and Phlebitis NUR-121
Antibiotics
  • Anti-infective Therapy Guidelines NUR-200
Chemotherapy and Biotherapy
  • Guidelines NUR-202
  • Administration via Central Line NUR-203
  • Administration via Peripheral Line NUR-204
  • Administration via Bolus Infusion NUR-205
  • Exposure or Spill NUR-206
  • Management of Extravasation NUR-207
  • Vesicants and Vascular Access Recommendations NUR-208
Nutritional Support/Fluid Support
  • Guidelines NUR-209
  • Enteral Feedings: Gravity Controlled & Pump Assisted NUR-210
  • Gastrostomy and Jejunostomy Care NUR-212
  • Hydration Therapy NUR-213
Pain Management 
  • Pain Management Guidelines NUR-216
Cardiac Infusions
  • Cardiac Inotropic Agents Guidelines NUR-217

B. CATHETERS

Peripheral Vein Catheter/Needle
Peripherally Inserted Central Catheter (PICC) and Midline Catheter
Central Venous Catheter (CVC)
  • Guidelines NUR-108
  • Vascular Access Device Dressing and Needleless Connector Change NUR-109
Vascular Access Port (VAP)
  • Non-Coring Needle Insertion, Removal and Dressing Change NUR-113
Pheresis Catheters

C. OTHER ADMINISTRATION ROUTES

  • Continuous Subcutaneous Infusions NUR-007
  • Subcutaneous Injections NUR-008
  • Intramuscular Injections NUR-009
  • Synchromed Pump: Accessing and Refilling Spinal Pumps NUR-011

D. CLINICAL GUIDELINES

  • Eculizumab (Soliris) and Ravulizumab (Ultomiris) Clinical Guideline for Home Intravenous Therapy CG-001 
  • Belimumab (Benlysta) Clinical Guideline for Home Intravenous Therapy CG-002 
  • Rozanolixizumab (Rystiggo) Clinical Guideline for Home Intravenous Therapy CG-003
  • Enjaymo (sutimlimab-jome) Clinical Guideline for Home Intravenous Therapy CG-004
  • Vedolizumab (Entyvio) Guideline for Home Intravenous Therapy CG-005 
  • Eptinezumab-jjmr (Vyepti) Clinical Guideline for Home Intravenous Therapy CG-006 
  • Ustekinumab (Stelara) Clinical Guideline for Home Intravenous Therapy CG-007 
  • Efgartigimod alfa-fcab (Vyvgart)/Efgartigimod alfa and Hyaluronidase-qvfc (Vyvgart Hytrulo) Clinical Guideline for Home Intravenous and Subcutaneous Therapy CG-008
  • Cinqair (Reslizumab) Clinical Guideline CG-010 
  • Infliximab (Remicade) and Biosimilars Clinical Guideline for Home Intravenous Therapy CG-011
  • Mirikizumab-mrkz (Omvoh) Clinical Guideline for Home Intravenous Therapy CG-012
  • Fecal Microbiota Live (Rebyota) Clinical Guideline for Home Administration CG-013
  • Risankizumab (Skyrizi-rzaa) Clinical Guideline for Home Intravenous Therapy CG-014
  • Bezlotoxumab (Zinplava) Clinical Guideline for Home Intravenous Therapy CG-015
  • Guselkumab (Tremfya) Clinical Guideline CG-016
  • Pemivibart (Pemgarda) Clinical Guideline for Home Intravenous Therapy CG-017
  • Teprotumumab-trbw (Tepezza) Clinical Guideline for Home Intravenous Therapy CG019
  • Ocrelizumab (Ocrevus) for Home Infusion Therapy and Ocrelizumab and Hyaluronidase-ocsq (Ocrevus Zunovo) for Home Subcutaneous Infusion CG020
  • Intravenous Albumin Administration NUR-222
  • Subcutaneous Hyqvia Infusion NUR-223
  • Clinical Guidelines for Outpatient R-EPOCH for Non-Hodgkins Lymphoma NUR-226
  • Clinical Guidelines for Intravenous Infliximab and Biosimilars NUR-227
  • Clinical Guidelines for Intravenous Trogarzo (Ibalizumab-uiyk) NUR-228
  • Guidelines for Outpatient Tepezza (Teprotumumab) Therapy NUR-229
  • Clinical Guidelines for Belimumab – Benlysta Injection NUR-231
  • Clinical Guidelines for Intravenous Anifrolumab-FNIA (Saphnelo) NUR-232
  • Guidelines for Outpatient Ocrelizumab (Ocrevus) Therapy NUR-233
  • Guidelines for Outpatient Krystexxa (Pegloticase) Therapy NUR-234
  • Clinical Guideline for Belatecept (Nulojix) NUR-235
  • Guidelines for Outpatient Blinatuomab NUR-236
  • Guidelines for Outpatient Abatacept (Orencia) NUR-238
  • Guidelines for Outpatient IV Yondelis (Trabectedin) NUR-240
  • Guidelines for Outpatient Intravenous Immune Globulin Therapy NUR-241
  • Guidelines for Outpatient Fulvestrant (Faslodex) IM Therapy NUR-243
  • Guidelines for Outpatient Subcutaneous Trastuzumab Hyaluronidase-Oysk (Hereptin Hylecta) NUR-244
  • Clinical Guideline for Outpatient Enzyme Replacement Therapy NUR-246
  • Guidelines for Outpatient IV Actemra (Tocilizumab) NUR-247
  • Guidelines for SC Pertuzumab-Traztuzumab-Hyaluronidase-ZZXF (Phesgo) NUR-248
  • Guideline for IV Simpopni Aria (Globimumab) Therapy NUR-250
  • Clinical Guidelines for IV Remdesivir for Treatment of COVID-19 in Outpatient Setting NUR-251
  • Guidelines for Outpatient IV Uplizna (Inebilizumab-cdon) Therapy NUR-252
  • Guidelines for Outpatient IV Keytruda (Pembrolizumab) NUR-253
  • Clinical Guidelines for IV Patisiran (Onpattro) NUR-254
  • Guidelines for IV Edaravone (Radicava) NUR-255
  • Guideline for Outpatient IV Alpha-1 Proteinase Inhibitors NUR-256
  • Guideline for Crizanlizumab-TMCA (Adakveo) NUR-257
  • Guideline for Outpatient IV Teplizumab (Tzield) NUR-258
  • Guideline for Outpatient Rituxan (Rituximab) and its Biosimilars Therapy NUR-259
  • Guidelines for Intravenous Amyloid Beta-Directed Therapies NUR-260
  • Guidelines for Outpatient Gazyva (Obinutuzumab) NUR-261
  • Guidelines for In-Home Intravenous Natalizumab (Tysabri) Therapy NUR-262
  • Guidelines for In-Home Intravenous Vyvgart Therapy NUR-263
  • Guidelines for In-Home Intravenous Spesolimab-sbzo (Spevigo) Therapy NUR-264

E. INVOICE RESOURCES

These Clinical Guidelines have been created by CarepathRx solely for its internal use and the use of its contracted clinical partners. All other use of these guidelines is prohibited without express written permission. Published as Clinical Guidelines, CarepathRx’s clinical partners may adopt these as policies subject to the partner’s policy adoption processes.

These Clinical Guidelines have been created using resources that were current as of the “Reviewed” date, noted at the beginning of the document. Clinicians should refer to the manufacturer’s Prescribing Information (or equivalent) for the most up-to-date information. While CarepathRx has published these Clinical Guidelines after a close review of available literature and a clinical review process, given the evolving nature and complexity of modern pharmaceutical products, CarepathRx does not and cannot warrant or guarantee that these Clinical Guidelines reflect the objectively best or highest standard of care at any given time.

Nothing within these Clinical Guidelines is intended to supersede or interfere with any individual clinician’s decision-making or professional judgment with respect to either (1) prescribing or dispensing the drug or product in question or (2) the overall treatment plan for an individual patient. 

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